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ZOLVIX® (Monepantel)
Product information on this website is for Non-U.S. residents only and is provided by Novartis Animal Health Inc. for general purposes only. Many veterinary products listed are available upon prescription only, and not all such products may be available in all countries. The product information is not intended to provide complete medical information. SHOULD YOUR ANIMAL HAVE A MEDICAL CONDITION, PROMPTLY SEE YOUR OWN VETERINARIAN. WE DO NOT OFFER PERSONALIZED MEDICAL DIAGNOSIS OR ANIMAL-SPECIFIC TREATMENT ADVICE. You should always obtain complete medical information about your veterinary product prescription (including their beneficial medical uses and possible adverse effects) by discussing the appropriate use of any veterinary product directly with the prescribing veterinarian.
Veterinary professionals may obtain complete medical information from the product's information leaflet. Information on these products may vary by country. Animal owners and veterinarians should check with local medical resources and regulatory authorities for information appropriate to their country. In addition, current regulations in many countries limit (or even prohibit in some instances) the ability of Novartis Animal Health Inc. to provide information and/or to respond directly to questions regarding its prescription products. Novartis Animal Health Inc., however, will respond to inquiries from and provide information to your qualified health care professional in accordance with local regulations.
Description
Product Type
Oral anthelmintic for the treatment of gastro-intestinal roundworms in sheep
Description and Composition
ZOLVIX® contains 25 mg/mL monepantel, the first member of the novel class of anthelmintics, the Amino-Acetonitrile Derivatives (AADs), discovered in the year 2000 and developed by Novartis Animal Health. ZOLVIX® is a convenient low volume, high safety margin (10x dose rate) oral drench suitable for the control of gastro-intestinal nematode parasites (roundworms) in all classes of sheep.
Properties
AADs have a completely unique mode of action compared to all other anthelmintics available on the market.
Monepantel causes a paralysis of the worms by binding to a specific receptor that is only found in nematode parasites (roundworms). It is believed that the high margin of safety in sheep and environmental safety is attributable to the fact that the specific receptor for the AADs has not been found in any animal species.
Indications
ZOLVIX® is a ready-to-use oral solution.
Dosage and Administration
Check dose rates and drench gun before treatment commences. The dose for sheep and lambs is 0.5 mL/5 kg (1 mL/10 kg) (equivalent to 2.5 mg monepantel/kg liveweight). Do not under dose. Drench sheep orally, using a Novartis recommended drench gun.
The recommended dose rates are :
|
Body weight (kg) |
Dose (mL) |
Doses 1 L pack |
Doses 2.5 L pack |
Doses 5 L pack |
|
10–15 |
1.5 |
660 |
1650 |
3300 |
|
16–20 |
2.0 |
500 |
1250 |
2500 |
|
21–25 |
2.5 |
400 |
1000 |
2000 |
|
26–30 |
3.0 |
330 |
825 |
1650 |
|
31–35 |
3.5 |
280 |
700 |
1400 |
|
36–40 |
4.0 |
250 |
625 |
1250 |
|
41–50 |
5.0 |
200 |
500 |
1000 |
|
51–60 |
6.0 |
160 |
400 |
800 |
|
61–70 |
7.0 |
140 |
350 |
700 |
|
71–80 |
8.0 |
125 |
300 |
625 |
Sheep in excess of 80 kg body weight should be dosed at 1 mL/10 kg.
Withdrawal periods
Withdrawal periods according to national registrations.
Special Precautions and Warnings
Safety directions: Keep out of reach of children. May cause mild skin irritation. Avoid skin contact. Monepantel may possibly affect the liver from repeated oral exposure at high doses. Handle with care. Do not contaminate ponds, waterways or ditches with the product or used container.
Environmental protection: Product is designed for biocidal action against gastro-intestinal roundworms (nematodes). Avoid contamination of any water supply with product or used containers.
Formulations and Packages
ZOLVIX® is available in 1 L, 2.5 L and 5 L OPTIVIX™ fully flexible packs.
U.S. Residents
This is an international website and is intended for residents outside the US.
If you are a Livestock Producer or Veterinarian in the USA, please visit our country specific website.
livestock.novartis.com
For U.S. Resident only
Locations
Headquartered in Basel, Switzerland, and present in almost 40 countries, Novartis Animal Health employs approximately 2,600 associates worldwide.
Partnerships
Novartis collaborates with many companies and academic institutions to develop new products, acquire platform technologies, and access new markets.
Product Availability
Please note that not all products listed within this site may be available in all countries. Also, prescribing information and indications for products may differ from country to country, so please consult your local veterinarian for local prescribing and any other information you may be interested in.